Prof. Dr. med. Monika Brüggemann

Facts

Phone: +49-431-500-24980
Affiliations: Clinic for Internal Medicine II, Hematology and Oncology / University Medical Center Schleswig-Holstein, Campus Kiel, Divison of Hematological Special Diagnostics / University Medical Center Schleswig-Holstein, Campus Kiel
Address: Langer Segen 8-10, 24105 Kiel

Curriculum vitae

Education/Training

Since 2015Head of Division of Specialized Hematology Diagnostics in the Department of Hematology, University Hospital Kiel
2011-2015Senior Physician, Department of Hematology, University Hospital Kiel
2010Board Certification as a Specialist in Laboratory Medicine
1999-2011Residency/Fellowship (Departments of Hematology, Laboratory Medicine, Immunology, Infection Medicine) University Hospital Kiel
1997-1998Internship/Residency, Department of Hematology, University Hospital Essen
1995-1996Internship/Residency, Department of Hematology and Oncology, Community Hospital, Duisburg 
1988-1995Medical School in Essen

Research Experience/Academic Appointments

2007Postdoctoral lecture qualification in Molecular Hematology 
Since 1998Clinical lecturer and Research Fellow, Department of Hematology, University Hospital Kiel
1996-1997PostDoc, Molecular Genetic Laboratory, Department of Hematology,  University of Göttingen, Germany
1993-1996Doctorate thesis, Department of Pediatrics, University Hospital Essen (Prof. Dr. U. Stephan)
Fields of InterestTranslational research related to molecular genetics and MRD diagnostics of lymphoproliferative diseases. 

Important Scientific Prizes/Functions

Since 2019Member of the Steering Committee of the Clinician-scientist Academy Kiel
Since 2019Chair of the Laboratory Working Group of the DGHO
Since 2019Member of the Doctorate Board of the Medical Faculty of the University Kiel
Since 2016Member of the Gender Equality Board of the Medical Faculty of the University Kiel
Since 2016Member of the Protocol Committee of the BFM-Study Group and of the FLOW-BFM Network
Since 2016Board member of the EuroFlow Consortium
Since 2015Board member of the European ESG/EuroMRD Consortium
Since 2012Scientific secretary and member of the Protocol Committee of the German Multicenter ALL Study Group (GMALL)
2011Fritz Acker Memorial Award for clinical research in hemato-oncology
Since 2006Member of the European EuroFlow Consortium
Since 2003Member of the European ESG/EuroMRD Consortium
Since 1999Coordinator of the MRD analyses within the German Multicenter ALL Study Group 
Since 1998Member of the European BIOMED-2/EuroClonality Consortium

Project-related publications

P1, P3, P4, INF, Z

The Gene Expression Classifier ALLCatchR Identifies B-cell Precursor ALL Subtypes and Underlying Developmental Trajectories Across Age

Beder T, Hansen BT, Hartmann AM, Zimmermann J, Amelunxen E, Wolgast N, Walter W, Zaliova M, Antić Ž, Chouvarine P, Bartsch L, Barz MJ, Bultmann M, Horns J, Bendig S, Kässens J, Kaleta C, Cario G, Schrappe M, Neumann M, Gökbuget N, Bergmann AK, Trka J, Haferlach C, Brüggemann M, Baldus CD, Bastian L.

HemaSphere
2023
P1, P3, P4, Z, INF

Developmental trajectories and cooperating genomic events define molecular subtypes of BCR::ABL1-positive ALL.

Bastian L, Beder T, Barz MJ, Bendig S, Bartsch L, Walter W, Wolgast N, Brändl B, Rohrandt C, Hansen BT, Hartmann AM, Iben K, Das Gupta D, Denker M, Zimmermann J, Wittig M, Chitadze G, Neumann M, Schneller F, Fiedler W, Steffen B, Stelljes M, Faul C, Schwartz S, Müller FJ, Cario G, Harder L, Haferlach C, Pfeifer H, Gökbuget N, Brüggemann M, Baldus CD.

P1, P3, P4, INF, Z

UBTF::ATXN7L3 gene fusion defines novel B cell precursor ALL subtype with CDX2 expression and need for intensified treatment

Bastian L, Hartmann AM, Beder T, Hänzelmann S, Kässens J, Bultmann M, Hoeppner MP, Franzenburg S, Wittig M, Franke F, Nagel I, Spielmann M, Reimer N, Busch H, Schwartz S, Steffen B, Viardot A, Döhner K, Kondakci M, Wulf G,  Wendelin K, Renzelmann A, Kiani A, Trautmann H, Neumann M, Gökbuget N, Brüggemann M, Baldus CD

Leukemia
2022
P1, P3, P4, Z

Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures

Schroeder MP, Bastian L, Eckert C, Gökbuget N, James AR, Tanchez JO, Schlee C, Isaakidis K, Häupl B, Baum K, Migueles Lozano OA, Kouidri K, Pan KT, Urlaub H, Schwartz S, Burmeister T, von Stackelberg A, Hoelzer D, Pfeiffer H, Rieger MA, Göllner S, Oellerich T, Horstmann M, Schrappe M, Wolf J, Kirschner-Schwabe R, Brüggemann M, Müller-Tidow C, Serve H, Neumann M, Baldus CD

P3

Standardized next-generation sequencing of immunoglobulin and T-cell receptor gene recombinations for MRD marker identification in acute lymphoblastic leukemia; a EuroClonality-NGS validation study

Brüggemann M, Kotrová M, Knecht H, Bartram J, Boudjogrha M, Bystry V, Fazio G, Froňková E, Giraud M, Grioni A, Hancock J, Herrmann D, Jiménez C, Krejci A, Moppett J, Reigl T, Salson M, Scheijen B, Schwarz M, Songia S, Svaton M, van Dongen JJM, Villarese P, Wakeman S, Wright G, Cazzaniga G, Davi F, García-Sanz R, Gonzalez D, Groenen PJTA, Hummel M, Macintyre EA, Stamatopoulos K, Pott C, Trka J, Darzentas N, Langerak AW, on behalf of the EuroClonality-NGS working group

Leukemia
2019
P1, P3, P4, Z

Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures

Schroeder MP, Bastian L, Eckert C, Gökbuget N, James AR, Tanchez JO, Schlee C, Isaakidis K, Häupl B, Baum K, Migueles Lozano OA, Kouidri K, Pan KT, Urlaub H, Schwartz S, Burmeister T, von Stackelberg A, Hoelzer D, Pfeiffer H, Rieger MA, Göllner S, Oellerich T, Horstman M, Schrappe M, Wolf J, Kirschner-Schwabe R, Brüggemann M, Müller-Tidow C, Serve H, Neumann M, Baldus CD

Participating Institutes